Analysis of 3D Printing Materials as Potential Radiological phantoms of Lung Organs for Medical Imaging purposes
Keywords:
3D printer, filament, radiology, phantom, lung, 3D printer, filament, radiology, phantom, lungAbstract
Research has been conducted to analyze and characterize ten 3D printing materials as potential Radiological Phantoms of Lung Organs. Eight filaments of PLA, ABS, HIPS, Carbon, Nylon, TPU, PETG, and Wood were printed using an FDM type 3D printer, and two resins, PLA resin and Water washable resin, were printed using an SLA type 3D printer. The phantoms were printed with thickness variations of 3 mm, 6 mm, and 9 mm. 8 parameters were used to obtain the best material, namely material density, CT number, electron density (Ne), effective electron density (EDG), electron density per volume (EDV), effective atomic number (Zeff), material constituent elements, and elastic Modulus. Based on comparing the values of 8 parameters, the most potential to be used as phantom material for lung organs is PLA.
References
Akhlaghi, P. H. M. Hakimabad and L. R. Motavalli. (2015). Determination of tissue equivalent materials of a physical 8-year-old phantom for use in computed tomography. Radiation Physics and Chemistry, 112: 169-176. https://doi.org/10.1016/j.radphyschem.2015.03.030
Alssabagh, M.; A. A. Tajuddin; M. A. Manap and R. Zainon. (2017). Evaluation of 3D printing materials for fabrication of a novel multi-functional 3D thyroid phantom for medical dosimetry and image quality. Radiation Physics and Chemistry, 135, 106-112 https://doi.org/10.1016/j.radphyschem.2017.02.009.
Chang, K. P.; S. H. Hung; Y. H. Chie; A. C. Shiau and R. J. Huang. (2012). A comparison of physical and dosimetric properties of lung substitute materials. Medical physics, 39(4): 2013-2020. https://doi.org/10.1118/1.3694097
Cui, J.; C. H. Lee; A. Delbos; J. J. McManus and A. J. Crosby. (2011). Cavitation rheology of the eye lens. Soft Matter, 7(17): 7827-7831. https://doi.org/10.1039/C1SM05340J
Danail, I.; B. Kristina; B. Ivan; P. Peycho; M. Giovanni; R. Paolo; D. L. Francesca; S. Antonio; V. Janne; B. Hilde; B. Alberto and B. Zhivko. (2018). Suitability of low density materials for 3D printing of physical breast phantoms. Physics in Medicine & Biology, 63(17): 175020 https://doi.org/10.1088/1361-6560/aad315
Fatima, F.; C. I. Irgananda; K. A. Wulan and F. A. Tabatya. (2021). Kekuatan Tekan Model Gigi Berbahan Dasar Self-Cured Acrylic Sebagai Media Pembelajaran Keterampilan Klinis Prostodonsia. E-Prodenta Journal of Dentistry, 5(2): 496 - 505. http://dx.doi.org/10.21776/ub.eprodenta.2021.005.02.6
Fujibuchi, T. (2021). Investigation of a method for creating neonatal chest phantom using 3D printer. In Journal of Physics: Conference Series, 1943(1): 012056 https://doi.org/10.1088/1742-6596/1943/1/012056
Gamex (A Sun Nuclear Company). (2015). CT Electron Density Phantom. https://www.sunnuclear.com/documents/datasheets/gammex/ct_electron_density_phantom.pdf
Gear, J. I.; C. Long; D. Rushforth; S. J. Chittenden; C. Cummings and G. D. Flux. (2014). Development of patient-specific molecular imaging phantoms using a 3D printer. Medical Physics., 41: 082502. https://doi.org/10.1118/1.4887854
Giacometti, V.; R. B. King; C. McCreery; F. Buchanan; P. Jeevanandam; S. Jain; A. R. Hounsell and C.K. McGarry. (2021). 3D-printed patient-specific pelvis phantom for dosimetry measurements for prostate stereotactic radiotherapy with dominant intraprostatic lesion boost. Physica Medica, 92: 8-14. https://doi.org/10.1016/j.ejmp.2021.10.018
Giron, H. I.; J. M, den Harder; G. J. Streekstra; J. Geleijns and W. J. Veldkamp. (2019). Development of a 3D printed anthropomorphic lung phantom for image quality assessment in CT. Physica Medica, 57: 47-57. https://doi.org/10.1016/j.ejmp.2018.11.015
Guswantoro, T.; A. S. Supratman and I. S. Asih. (2020). Karakterisasi Alginat Sebagai Bahan Setara Dengan Jaringan Lunak Untuk Radioterapi. EduMatSains: Jurnal Pendidikan, Matematika dan Sains, 4(2): 125-138. https://doi.org/10.33541/edumatsains.v4i2.1378
Handoko, A.; H. Hidayatullah; E. Hidayanto and V. Richardina. (2018). Analisis keakuratan verifikasi dosis dengan menggunakan perbandingan phantom standar dan phantom replica. Youngster Physics Journal, 7(1): 1-10. https://ejournal3.undip.ac.id/index.php/bfd/article/view/20857
Hazelaar, C.; M. V. Eijnatten; M. Dahele; J. Wolff; T. Forouzanfar; B. Slotman and W.F.A.R. Verbakel. (2018). Using 3D printing techniques to create an anthropomorphic thorax phantom for medical imaging purposes. Medical Physics, 45: 92-100. https://doi.org/10.1002/mp.12644
ICRU—International Commission on Radiation Units and Measurements. (1989). Tissue substitutes in radiation dosimetry and measurement, ICRU Report No. 44, os-23, 1. https://www.icru.org/report/tissue-substitutes-in-radiation-dosimetry-and-measurement-report-44/
Ikejimba, L. C.; C. G. Graff; S. Rosenthal; A. Badal, B. Ghammraoui, J. Y. Lo, and S. J. Glick. (2017). A novel physical anthropomorphic breast phantom for 2D and 3D x-ray imaging. Medical Physics, 44: 407-416. https://doi.org/10.1002/mp.12062
Jansen, L. E.; N. P. Birch; J. D. Schiffman; A. J. Crosby and S. R. Peyton. (2015). Mechanics of intact bone marrow. Journal of the Mechanical Behavior of Biomedical Materials, 50: 299-307. https://doi.org/10.1016/j.jmbbm.2015.06.023
Kaginelli, S. B.; T. Rajeshwari; B. R. Kerur and A. S. Kumar. (2009). Effective atomic numbers and electron density of dosimetric material. Journal of Medical Physics/Association of Medical Physicists of India, 34(3): 176. https://doi.org/10.4103%2F0971-6203.54853
Khoramian, D.; S. Sistani and R. A. Firouzjah. (2019). Assessment and comparison of radiation dose and image quality in multi-detector CT scanners in non-contrast head and neck examinations. Polish Journal of Radiology, 84: e61-e67. https://doi.org/10.5114/pjr.2019.82743
Listiyani, I. L.; A. Nismayanti; M. Maskur; K. Kasman; M. S. Ulum and A. R. Rahman. (2021). Analisis Noise Level Hasil Citra CT-Scan Pada Phantom Kepala Dengan Variasi Tegangan Tabung Dan Ketebalan Irisan, Gravitasi, 20(1): 5 - 9. https://doi.org/10.22487/gravitasi.v20i1.15517
McGarry, C. K.; L. J. Grattan; A. M. Ivory; F. Leek; G. P. Liney; Y. Liu and C. H. Clark. (2020). Tissue mimicking materials for imaging and therapy phantoms: a review: Physics in Medicine & Biology, 65(23). https://doi.org/10.1088/1361-6560/abbd17
McKee, C.T.; J.A. Last; P. Russell and C.J. Murphy. (2011). Indentation versus tensile measurements of Young's modulus for soft biological tissues. Tissue Engineering Part B: Reviews, 17(3): 155-164. https://doi.org/10.1089%2Ften.teb.2010.0520
Meilinda, T.; E. Hidayanto and Z. Arifin. (2014). Pengaruh Perubahan Faktor Eksposi Terhadap Nilai CT Number. Youngster Physics Journal, 3(3): 269-278 https://ejournal3.undip.ac.id/index.php/bfd/article/view/5945
Mufida, W.; A. P. Utami and S. N. Dewi. (2020). Pembuatan Phantom Radiologi Berbahan Dasar Kayu Lokal sebagai Pengganti Tulang Manusia, Jurnal Imejing Diagnostik , 6(1): 7-10 https://doi.org/10.31983/jimed.v6i1.5404
Park, S. Y.; C. H. Choi; J. M. Park; M. Chun; J. H. Han and J. I. Kim. (2016). A patient-specific polylactic acid bolus made by a 3D printer for breast cancer radiation therapy. PloS one, 11(12): e0168063 https://doi.org/10.1371/journal.pone.0168063
Purwantiningsi, P. and Lesmana, H. (2019). Pengukuran Nilai CT Number Pada Phantom CIRS 062m sebagai Data Input Kalkulasi Dosis Program ISIS 3D di Treatment Planning System. Jurnal Ilmiah Giga, 17(2): 70-78 http://journal.unas.ac.id/giga/article/viewFile/541/428
Saito, M. and S. Sagara. (2017). A simple formulation for deriving effective atomic numbers via electron density calibration from dual‐energy CT data in the human body. Medical Physics, 44(6): 2293-2303. https://doi.org/10.1002/mp.12176
Sari, D. A.; E. Setiawati and Z. Arifin. (2018). Analisis Nilai Computed Tomography Dose Index (CTDI) Phantom Kepala Menggunakan CT Dose Profiler Dengan Variasi Pitch. Berkala Fisika, 23(2): 42-48. https://ejournal.undip.ac.id/index.php/berkala_fisika/article/view/30622
Seeram, E. (2016). Computed Tomography: Physical Principles. Clinical Applications, And Quality Control, Fourth. Vol. Fourth. St. Louis, Missouri: Elsevier.
Sicard, D.; A. J. Haak; K. M. Choi; A. R. Craig; L. E. Fredenburgh and D. J. Tschumperlin. (2018). Aging and anatomical variations in lung tissue stiffness. American Journal of Physiology-Lung Cellular and Molecular Physiology, 314(6): L946-L955. https://doi.org/10.1152/ajplung.00415.2017
Yunus, B. and B. Murtala. (2010). Pemanfaatan hounsfield unit pada CT-scan dalam menentukan kepadatan tulang rahang untuk pemasangan implan gigi, Journal of Dentomaxillofacial Science, 9(1): 34-38. https://jdmfs.org/index.php/jdmfs/article/view/230
Zhang, F.; H. Zhang; H. Zhao; Z. He; L. Shi and Y. He. (2019). Design and fabrication of a personalized anthropomorphic phantom using 3D printing and tissue equivalent materials. Quantitative imaging in medicine and surgery, 9(1): 94-100. https://doi.org/10.21037%2Fqims.2018.08.01
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